Bone Marrow Transplantation and CAR T-cell therapy

Target Audience:
Hematologists, oncologists

Type of Education Activity:
  • Offsite observership at Sheba – individual
  • The observership will include the following treatments:

  • Autologous and allogeneic stem cell transplantations from sibling, matched, and mismatched donors
  • Non-T-depleted-haploidentical transplants and cord blood transplantation for all types of hematological malignancies as well as non-malignant hematological disorders
  • Advanced cellular-based immunotherapies, including donor lymphocyte infusions and Chimeric antigen receptor-based therapies for lymphoma, myeloma, and also acute leukemia, mainly lymphatic but also a subtype of acute myelogenous leukemia.

Level: Basic – Advanced

Number of participants:
  • Offsite observership at Sheba: 1-2

Duration:
  • Offsite observership at Sheba: 2-4 weeks

Objectives:

  • Describing the indications and contraindications for BMT
  • Describing the indications and contraindications for CAR T-cell therapy
  • Reviewing the short and long-term complications of BMT and CAR T-cell therapy
  • Reviewing the latest protocols for BMT and CAR T-cell therapy

Main topics

  • Indications for BMT
  • CAR T-cell therapy principles and practice
  • BMT and CAR T-cell therapy case discussions
  • Early complications post BMT
  • Early complications post CAR T-cell therapy
  • Management of GvHD
  • Management of long-term complications

Training Methodology:

  • Ward rounds
  • Outpatient and day care unit management – observation
  • Clinical case discussions
* The course structure serves as a guideline and can be modified and tailored according to the needs and objectives of each client.

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